| Reaction Details |
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 | Report a problem with these data |
| Target | Replicative DNA helicase |
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| Ligand | BDBM50178993 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_338400 (CHEMBL866546) |
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| IC50 | >100000±n/a nM |
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| Citation |  McKay, GA; Reddy, R; Arhin, F; Belley, A; Lehoux, D; Moeck, G; Sarmiento, I; Parr, TR; Gros, P; Pelletier, J; Far, AR Triaminotriazine DNA helicase inhibitors with antibacterial activity. Bioorg Med Chem Lett16:1286-90 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Replicative DNA helicase |
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| Name: | Replicative DNA helicase |
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| Synonyms: | n/a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 51573.81 |
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| Organism: | Pseudomonas aeruginosa |
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| Description: | ChEMBL_338400 |
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| Residue: | 464 |
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| Sequence: | MNEITSPEQYDLETTALKVPPHSIEAEQAVLGGLMLDNNAWERVSDSVSDGDFYRHDHRL
IFRAIYKLAEANQPIDVVTLSEQLEKEGQLAQVGGLAYLGELAKNIPSVANIKAYAQIIR
ERATLRQLIGISNEIADSAFHPEGRGANEILDEAERKIFEVAEARPKTGGPVGISDILVK
TIDRIDYLFNTTEALTGVSTGFTDLDEKTSGLQPADLIIVAGRPSMGKTTFAMNLVENAV
MRTDKAVLVYSLEMPSDSIVMRMLSSLGRIDQTKVRSGKLDDEDWPRLTSAINLLNDKKL
FIDDTAGISPSEMRARTRRLVREHGDLALIMIDYLQLMQIPGSSGDNRTNEISEISRSLK
ALAKEFNCPVIALSQLNRSLEQRPNKRPVNSDLRESGAIEQDADVIMFVYRDEVYHPETE
FKGVAEIIIGKQRNGPIGTVRLAFIGKYTRFENLAAGMYNFEDE
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| BDBM50178993 |
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| n/a |
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| Name | BDBM50178993 |
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| Synonyms: | CHEMBL204595 | N-(2-morpholinoethyl)-N',N''-diphenyl-[1,3,5]triazine-2,4,6-triamine | N2-(2-morpholinoethyl)-N4,N6-diphenyl-1,3,5-triazine-2,4,6-triamine | cid_1095342 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H25N7O |
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| Mol. Mass. | 391.4695 |
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| SMILES | C(CN1CCOCC1)Nc1nc(Nc2ccccc2)nc(Nc2ccccc2)n1 |
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| Structure | 
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