| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity protein phosphatase 3 |
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| Ligand | BDBM50179008 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_339771 (CHEMBL862182) |
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| IC50 | >80000±n/a nM |
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| Citation |  Cui, L; Na, M; Oh, H; Bae, EY; Jeong, DG; Ryu, SE; Kim, S; Kim, BY; Oh, WK; Ahn, JS Protein tyrosine phosphatase 1B inhibitors from Morus root bark. Bioorg Med Chem Lett16:1426-9 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Dual specificity protein phosphatase 3 |
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| Name: | Dual specificity protein phosphatase 3 |
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| Synonyms: | DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR |
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| Type: | Hydrolase |
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| Mol. Mass.: | 20480.58 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 185 |
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| Sequence: | MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVL
NAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRV
LVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKE
GKLKP
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| BDBM50179008 |
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| n/a |
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| Name | BDBM50179008 |
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| Synonyms: | CHEMBL204813 | sanggenon C |
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| Type | Small organic molecule |
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| Emp. Form. | C40H36O12 |
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| Mol. Mass. | 708.7066 |
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| SMILES | [#6]\[#6](-[#6])=[#6]/[#6][C@]12[#8]-c3cc(-[#8])c(-[#6@H]-4-[#6]=[#6](-[#6])-[#6]-[#6@@H](-[#6@H]-4-[#6](=O)-c4ccc(-[#8])cc4-[#8])-c4ccc(-[#8])cc4-[#8])c(-[#8])c3-[#6](=O)[C@@]1([#8])[#8]-c1cc(-[#8])ccc21 |r,t:13| |
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| Structure | 
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