| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Retinoic acid receptor RXR-beta |
|---|
| Ligand | BDBM50179130 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_349698 (CHEMBL866289) |
|---|
| EC50 | 151±n/a nM |
|---|
| Citation |  Farmer, LJ; Marron, KS; Canan Koch, SS; Hwang, CK; Kallel, EA; Zhi, L; Nadzan, AM; Robertson, DW; Bennani, YL Aza-retinoids as novel retinoid X receptor-specific agonists. Bioorg Med Chem Lett16:2352-6 (2006) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Retinoic acid receptor RXR-beta |
|---|
| Name: | Retinoic acid receptor RXR-beta |
|---|
| Synonyms: | NR2B2 | Nuclear receptor subfamily 2 group B member 2 | RXRB | RXRB_HUMAN | Retinoic acid receptor RXR-beta | Retinoid X receptor beta | Retinoid receptor |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 56932.89 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_39045 |
|---|
| Residue: | 533 |
|---|
| Sequence: | MSWAARPPFLPQRHAAGQCGPVGVRKEMHCGVASRWRRRRPWLDPAAAAAAAVAGGEQQT
PEPEPGEAGRDGMGDSGRDSRSPDSSSPNPLPQGVPPPSPPGPPLPPSTAPSLGGSGAPP
PPPMPPPPLGSPFPVISSSMGSPGLPPPAPPGFSGPVSSPQINSTVSLPGGGSGPPEDVK
PPVLGVRGLHCPPPPGGPGAGKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYS
CRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDKDGDGEGAGGAPEEMP
VDRILEAELAVEQKSDQGVEGPGGTGGSGSSPNDPVTNICQAADKQLFTLVEWAKRIPHF
SSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFDRV
LTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEVEVLREKVYASLETYCKQKYP
EQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQLA
|
|
|
|---|
| BDBM50179130 |
|---|
| n/a |
|---|
| Name | BDBM50179130 |
|---|
| Synonyms: | (2E,4E)-6-((3,5-di-tert-butylphenyl)(propyl)amino)-3-methyl-6-oxohexa-2,4-dienoic acid | CHEMBL206005 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H35NO3 |
|---|
| Mol. Mass. | 385.5396 |
|---|
| SMILES | CCCN(C(=O)\C=C\C(\C)=C\C(O)=O)c1cc(cc(c1)C(C)(C)C)C(C)(C)C |
|---|
| Structure | 
|
|---|
Search and Browse
