| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM50179187 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_325358 (CHEMBL861058) |
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| IC50 | 30±n/a nM |
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| Citation |  Balboni, G; Guerrini, R; Salvadori, S; Negri, L; Giannini, E; Bryant, SD; Jinsmaa, Y; Lazarus, LH Conversion of the potent delta-opioid agonist H-Dmt-Tic-NH-CH(2)-bid into delta-opioid antagonists by N(1)-benzimidazole alkylation(1). J Med Chem48:8112-4 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 11165.58 |
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| Organism: | GUINEA PIG |
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| Description: | P97266 |
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| Residue: | 98 |
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| Sequence: | YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSI
FTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
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|
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| BDBM50179187 |
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| n/a |
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| Name | BDBM50179187 |
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| Synonyms: | CHEMBL197183 | ethyl 2-(2-(((S)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamido)methyl)-1H-benzo[d]imidazol-1-yl)acetate |
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| Type | Small organic molecule |
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| Emp. Form. | C33H37N5O5 |
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| Mol. Mass. | 583.6774 |
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| SMILES | CCOC(=O)Cn1c(CNC(=O)[C@@H]2Cc3ccccc3CN2C(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)nc2ccccc12 |
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| Structure | 
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