| Reaction Details |
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 | Report a problem with these data |
| Target | Bile salt-activated lipase |
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| Ligand | BDBM50179314 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_325182 (CHEMBL861460) |
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| Ki | >50000±n/a nM |
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| Citation |  Pietsch, M; Gütschow, M Synthesis of tricyclic 1,3-oxazin-4-ones and kinetic analysis of cholesterol esterase and acetylcholinesterase inhibition. J Med Chem48:8270-88 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Bile salt-activated lipase |
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| Name: | Bile salt-activated lipase |
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| Synonyms: | CEL | CEL_BOVIN | Cholesterol esterase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 65152.77 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_154778 |
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| Residue: | 597 |
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| Sequence: | LGASRLGPSPGCLAVASAAKLGSVYTEGGFVEGVNKKLSLFGDSIDIFKGIPFAAAPKAL
EKPERHPGWQGTLKAKSFKKRCLQATLTQDSTYGNEDCLYLNIWVPQGRKEVSHDLPVMI
WIYGGAFLMGASQGANFLSNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDSNLPGNY
GLWDQHMAIAWVKRNIEAFGGDPDNITLFGESAGGASVSLQTLSPYNKGLIKRAISQSGV
GLCPWAIQQDPLFWAKRIAEKVGCPVDDTSKMAGCLKITDPRALTLAYKLPLGSTEYPKL
HYLSFVPVIDGDFIPDDPVNLYANAADVDYIAGTNDMDGHLFVGMDVPAINSNKQDVTEE
DFYKLVSGLTVTKGLRGANATYEVYTEPWAQDSSQETRKKTMVDLETDILFLIPTKIAVA
QHKSHAKSANTYTYLFSQPSRMPIYPKWMGADHADDLQYVFGKPFATPLGYRAQDRTVSK
AMIAYWTNFARTGDPNTGHSTVPANWDPYTLEDDNYLEINKQMDSNSMKLHLRTNYLQFW
TQTYQALPTVTSAGASLLPPEDNSQASPVPPADNSGAPTEPSAGDSEVAQMPVVIGF
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|
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| BDBM50179314 |
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| n/a |
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| Name | BDBM50179314 |
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| Synonyms: | 5,6,7,8-tetrahydro-2-(dimethylamino)-7-(2-methyl-propyl)-4H-pyrido[4',3':4,5]thieno[2,3-d][1,3]oxazin-4-one | CHEMBL107521 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H21N3O2S |
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| Mol. Mass. | 307.411 |
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| SMILES | CC(C)CN1CCc2c(C1)sc1nc(oc(=O)c21)N(C)C |
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| Structure | 
|
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