| Reaction Details |
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 | Report a problem with these data |
| Target | Phospholipase B |
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| Ligand | BDBM50084949 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_330127 (CHEMBL858987) |
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| IC50 | >250000±n/a nM |
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| Citation |  Ng, CK; Obando, D; Widmer, F; Wright, LC; Sorrell, TC; Jolliffe, KA Correlation of antifungal activity with fungal phospholipase inhibition using a series of bisquaternary ammonium salts. J Med Chem49:811-6 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Phospholipase B |
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| Name: | Phospholipase B |
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| Synonyms: | PLB | PLB1 | PLB1_CRYNB |
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| Type: | PROTEIN |
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| Mol. Mass.: | 68557.23 |
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| Organism: | Cryptococcus neoformans |
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| Description: | ChEMBL_330127 |
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| Residue: | 637 |
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| Sequence: | MSIITTAFALSLLATTAFAVPPETPRIELQAERGLGDQSYAPWQVDCPSNVTWIRNATTG
LGTGERAYIEAREKLVQPAIEQMMAARGLETPPRTPVIGVALAGGGYRAMLTGLGGIMGM
MNESTEASQSETGGWLDGVSYWSGLSGGSWATGSFMSNGGQLPTTLLENLWNIDSNLVFP
DDGKLSFYTNLYTETNAKSDLGFPVQITDIWGLAIGSHVLPEPYQLSNTPNLTFSSLPSV
VAALGNASLPMPIIVAADRKRREAGELVIAENATVWEFTPYEFGSWAFGSQYKSPGAFTP
IEYLGTSVDDGSPNGTCWKGFDQLSFVMGTSATLFNGAFLELNGTDSGLLTNLITAFLAD
LGEDQADISRIPNSFSNYNSGENPIYNLTYITLVDAGETNQNIPLEPLLVPTRDVDAIVA
FDSSYDSDYIWPNGTALRTTYERAKILAEHENTRVLMPEVPSMNGFVNGGYNSRPTFFGC
NDTTTPVIIYIPSYPWSFAANTSTYQLSYENNEANEMLLNGMRSLTLNHSVPTWPTCFAC
ALTDRSFMYTSENRSTTCQECFDTWCWAGDDNTTEPANYEPVINSVPPWLIANNLSIGMA
DAPGSNESTAGTASSGAAKMGVGMGMVALTAGLGLML
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| BDBM50084949 |
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| n/a |
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| Name | BDBM50084949 |
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| Synonyms: | 1,12-Bis(N-methylpyrrolidinium)dodecane dibromide | 1-methyl-1-[3-(1-methylpyrrolidinium-1-yl)pentyl] pyrrolidinium dibromide | CHEMBL149661 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H46N2 |
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| Mol. Mass. | 338.6129 |
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| SMILES | C[N+]1(CCCCCCCCCCCC[N+]2(C)CCCC2)CCCC1 |
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| Structure | 
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