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TargetDNA polymerase beta
LigandBDBM50181922
Substrate/Competitorn/a
Meas. Tech.ChEMBL_345624
IC50>10000±n/a nM
Citation Ishida TSuzuki THirashima SMizutani KYoshida AAndo IIkeda SAdachi THashimoto H Benzimidazole inhibitors of hepatitis C virus NS5B polymerase: identification of 2-[(4-diarylmethoxy)phenyl]-benzimidazole. Bioorg Med Chem Lett 16:1859-63 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
DNA polymerase beta
Name:DNA polymerase beta
Synonyms:DNA polymerase beta (Pol β)
Type:Protein
Mol. Mass.:38188.76
Organism:Homo sapiens (Human)
Description:n/a
Residue:335
Sequence:
MSKRKAPQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAK
KLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIK
TLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGS
FRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQ
LPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRP
LGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50181922
n/a
NameBDBM50181922
Synonyms:2-(4-(bis(3-fluorophenyl)methoxy)phenyl)-1-cyclohexyl-1H-benzo[d]imidazole-5-carboxylic acid | CHEMBL425769
TypeSmall organic molecule
Emp. Form.C33H28F2N2O3
Mol. Mass.538.5838
SMILESOC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccc(OC(c2cccc(F)c2)c2cccc(F)c2)cc1
Structure
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