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TargetDNA polymerase beta
LigandBDBM50181929
Substrate/Competitorn/a
Meas. Tech.ChEMBL_345624
IC50>10000±n/a nM
Citation Ishida TSuzuki THirashima SMizutani KYoshida AAndo IIkeda SAdachi THashimoto H Benzimidazole inhibitors of hepatitis C virus NS5B polymerase: identification of 2-[(4-diarylmethoxy)phenyl]-benzimidazole. Bioorg Med Chem Lett 16:1859-63 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
DNA polymerase beta
Name:DNA polymerase beta
Synonyms:DNA polymerase beta (Pol β)
Type:Protein
Mol. Mass.:38188.76
Organism:Homo sapiens (Human)
Description:n/a
Residue:335
Sequence:
MSKRKAPQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAK
KLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIK
TLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGS
FRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQ
LPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRP
LGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50181929
n/a
NameBDBM50181929
Synonyms:1-cyclohexyl-2-(4-(dip-tolylmethoxy)phenyl)-1H-benzo[d]imidazole-5-carboxylic acid | CHEMBL203772
TypeSmall organic molecule
Emp. Form.C35H34N2O3
Mol. Mass.530.6561
SMILESCc1ccc(cc1)C(Oc1ccc(cc1)-c1nc2cc(ccc2n1C1CCCCC1)C(O)=O)c1ccc(C)cc1
Structure
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