| Reaction Details |
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 | Report a problem with these data |
| Target | Potassium voltage-gated channel subfamily A member 2 |
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| Ligand | BDBM50182585 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_334898 (CHEMBL861276) |
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| EC50 | 1400±n/a nM |
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| Citation |  Harvey, AJ; Baell, JB; Toovey, N; Homerick, D; Wulff, H A new class of blockers of the voltage-gated potassium channel Kv1.3 via modification of the 4- or 7-position of khellinone. J Med Chem49:1433-41 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Potassium voltage-gated channel subfamily A member 2 |
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| Name: | Potassium voltage-gated channel subfamily A member 2 |
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| Synonyms: | HBK5 | HUKIV | KCNA2 | KCNA2_HUMAN | NGK1 | Potassium voltage-gated channel subfamily A member 2 | Voltage-gated potassium channel | Voltage-gated potassium channel subunit Kv1.2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 56695.97 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_334898 |
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| Residue: | 499 |
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| Sequence: | MTVATGDPADEAAALPGHPQDTYDPEADHECCERVVINISGLRFETQLKTLAQFPETLLG
DPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFYELGE
EAMEMFREDEGYIKEEERPLPENEFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVSF
CLETLPIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVR
FFACPSKAGFFTNIMNIIDIVAIIPYFITLGTELAEKPEDAQQGQQAMSLAILRVIRLVR
VFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERESQFPS
IPDAFWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRE
TEGEEQAQYLQVTSCPKIPSSPDLKKSRSASTISKSDYMEIQEGVNNSNEDFREENLKTA
NCTLANTNYVNITKMLTDV
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| BDBM50182585 |
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| n/a |
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| Name | BDBM50182585 |
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| Synonyms: | 5-acetyl-7-(4'-bromo)benzyloxy-6-hydroxy-4-methoxybenzofuran | CHEMBL426482 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H15BrO5 |
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| Mol. Mass. | 391.213 |
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| SMILES | COc1c(C(C)=O)c(O)c(OCc2ccc(Br)cc2)c2occc12 |
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| Structure | 
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