Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetBeta-glucosidase
LigandBDBM18351
Substrate/Competitorn/a
Meas. Tech.ChEMBL_344324 (CHEMBL867768)
Ki 12000±n/a nM
Citation Greimel, P; Häusler, H; Lundt, I; Rupitz, K; Stütz, AE; Tarling, CA; Withers, SG; Wrodnigg, TM Fluorescent glycosidase inhibiting 1,5-dideoxy-1,5-iminoalditols. Bioorg Med Chem Lett16:2067-70 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Beta-glucosidase
Name:Beta-glucosidase
Synonyms:BGLS_RHIRD | cbg-1
Type:PROTEIN
Mol. Mass.:88266.88
Organism:Agrobacterium tumefaciens
Description:ChEMBL_1366789
Residue:818
Sequence:
MIDDILDKMTLEEQVSLLSGADFWTTVAIERLGVPKIKVTDGPNGARGGGSLVGGVKSAC
FPVAIALGATWDPELIERAGVALGGQAKSKGASVLLAPTVNIHRSGLNGRNFECYSEDPA
LTAACAVAYINGVQSQGVAATIKHFVANESEIERQTMSSDVDERTLREIYLPPFEEAVKK
AGVKAVMSSYNKLNGTYTSENPWLLTKVLREEWGFDGVVMSDWFGSHSTAETINAGLDLE
MPGPWRDRGEKLVAAVREGKVKAETVRASARRILLLLERVGAFEKAPDLAEHALDLPEDR
ALIRQLGAEGAVLLKNDGVLPLAKSSFDQIAVIGPNAASARVMGGGSARIAAHYTVSPLE
GIRAALSNANSLRHAVGCNNNRLIDVFSGEMTVEYFKGRGFESRPVHVETVEKGEFFWFD
LPSGDLDLADFSARMTATFVPQETGEHIFGMTNAGLARLFVDGELVVDGYDGWTKGENFF
GTANSEQRRAVTLGAARRYRVVVEYEAPKASLDGINICALRFGVEKPLGDAGIAEAVETA
RKSDIVLLLVGREGEWDTEGLDLPDMRLPGRQEELIEAVAETNPNVVVVLQTGGPIEMPW
LGKVRAVLQMWYPGQELGNALADVLFGDVEPAGRLPQTFPKALTDNSAITDDPSIYPGQD
GHVRYAEGIFVGYRHHDTREIEPLFPFGFGLGYTRFTWGAPQLSGTEMGADGLTVTVDVT
NIGDRAGSDVVQLYVHSPNARVERPFKELRAFAKLKLAPGATGTAVLKIAPRDLAYFDVE
AGRFRADAGKYELIVAASAIDIRASVSIHLPVDHVMEP
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM18351
n/a
NameBDBM18351
Synonyms:(2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-triol, 10 | (2R,3R,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol | 1-Deoxynojirimycin | 1-deoxynojirimycin (DNJ) | CHEMBL307429 | US20230339856, Compound DNJ | US9181184, 1 | dNM
Typenatural product
Emp. Form.C6H13NO4
Mol. Mass.163.1717
SMILESOC[C@H]1NC[C@H](O)[C@@H](O)[C@@H]1O
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: