| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Mu-type opioid receptor |
|---|
| Ligand | BDBM50182939 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_349389 (CHEMBL865710) |
|---|
| EC50 | 2±n/a nM |
|---|
| Citation |  Breslin, HJ; Cai, C; Miskowski, TA; Coutinho, SV; Zhang, SP; Hornby, P; He, W Identification of potent phenyl imidazoles as opioid receptor agonists. Bioorg Med Chem Lett16:2505-8 (2006) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Mu-type opioid receptor |
|---|
| Name: | Mu-type opioid receptor |
|---|
| Synonyms: | M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 11165.58 |
|---|
| Organism: | GUINEA PIG |
|---|
| Description: | P97266 |
|---|
| Residue: | 98 |
|---|
| Sequence: | YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSI
FTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
|
|
|
|---|
| BDBM50182939 |
|---|
| n/a |
|---|
| Name | BDBM50182939 |
|---|
| Synonyms: | (S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-1-((S)-2-(4-phenyl-1H-imidazol-2-yl)piperidin-1-yl)propan-1-one | CHEMBL377069 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H30N4O2 |
|---|
| Mol. Mass. | 418.5313 |
|---|
| SMILES | Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCCC[C@H]1c1nc(c[nH]1)-c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
