| Reaction Details |
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 | Report a problem with these data |
| Target | Cytochrome P450 2J2 |
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| Ligand | BDBM50183077 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_350781 (CHEMBL869679) |
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| IC50 | 1300±n/a nM |
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| Citation |  Lafite, P; Dijols, S; Buisson, D; Macherey, AC; Zeldin, DC; Dansette, PM; Mansuy, D Design and synthesis of selective, high-affinity inhibitors of human cytochrome P450 2J2. Bioorg Med Chem Lett16:2777-80 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cytochrome P450 2J2 |
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| Name: | Cytochrome P450 2J2 |
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| Synonyms: | CP2J2_HUMAN | CYP2J2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 57623.04 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P51589 |
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| Residue: | 502 |
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| Sequence: | MLAAMGSLAAALWAVVHPRTLLLGTVAFLLAADFLKRRRPKNYPPGPWRLPFLGNFFLVD
FEQSHLEVQLFVKKYGNLFSLELGDISAVLITGLPLIKEALIHMDQNFGNRPVTPMREHI
FKKNGLIMSSGQAWKEQRRFTLTALRNFGLGKKSLEERIQEEAQHLTEAIKEENGQPFDP
HFKINNAVSNIICSITFGERFEYQDSWFQQLLKLLDEVTYLEASKTCQLYNVFPWIMKFL
PGPHQTLFSNWKKLKLFVSHMIDKHRKDWNPAETRDFIDAYLKEMSKHTGNPTSSFHEEN
LICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAARESMP
YTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDT
FNPDHFLENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEKLS
LKFRMGITISPVSHRLCAVPQV
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| BDBM50183077 |
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| n/a |
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| Name | BDBM50183077 |
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| Synonyms: | 4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)-1-(4-(2-hydroxyethyl)phenyl)butan-1-one | CHEMBL207389 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H35NO3 |
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| Mol. Mass. | 457.6038 |
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| SMILES | OCCc1ccc(cc1)C(=O)CCCN1CCC(CC1)C(O)(c1ccccc1)c1ccccc1 |
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| Structure | 
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