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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Reverse transcriptase/RNaseH | ||
| Ligand | BDBM50183195 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_355438 (CHEMBL868998) | ||
| IC50 | >5000±n/a nM | ||
| Citation |  Muraglia, E; Kinzel, OD; Laufer, R; Miller, MD; Moyer, G; Munshi, V; Orvieto, F; Palumbi, MC; Pescatore, G; Rowley, M; Williams, PD; Summa, V Tetrazole thioacetanilides: potent non-nucleoside inhibitors of WT HIV reverse transcriptase and its K103N mutant. Bioorg Med Chem Lett16:2748-52 (2006) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Reverse transcriptase/RNaseH | |||
| Name: | Reverse transcriptase/RNaseH | ||
| Synonyms: | HIV-1 Reverse Transcriptase RNase H | Human immunodeficiency virus type 1 reverse transcriptase | Reverse transcriptase/RNaseH | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 65229.15 | ||
| Organism: | Human immunodeficiency virus 1 | ||
| Description: | ChEMBL_1473730 | ||
| Residue: | 566 | ||
| Sequence: |
| ||
| BDBM50183195 | |||
| n/a | |||
| Name | BDBM50183195 | ||
| Synonyms: | 2-(1-mesityl-1H-tetrazol-5-ylthio)-N-(4-nitrophenyl)acetamide | CHEMBL205041 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C18H18N6O3S | ||
| Mol. Mass. | 398.439 | ||
| SMILES | Cc1cc(C)c(c(C)c1)-n1nnnc1SCC(=O)Nc1ccc(cc1)[N+]([O-])=O |(-7.23,-36.04,;-6.89,-34.53,;-8.03,-33.49,;-7.7,-31.98,;-8.83,-30.95,;-6.23,-31.52,;-5.09,-32.55,;-3.63,-32.08,;-5.42,-34.07,;-5.91,-30.01,;-6.93,-28.86,;-6.16,-27.53,;-4.65,-27.85,;-4.5,-29.38,;-3.17,-30.16,;-1.83,-29.39,;-.5,-30.16,;-.5,-31.7,;.83,-29.39,;2.17,-30.17,;2.16,-31.71,;3.49,-32.48,;4.83,-31.71,;4.82,-30.16,;3.49,-29.4,;6.16,-32.49,;6.16,-34.03,;7.5,-31.72,)| | ||
| Structure | 
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