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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Reverse transcriptase/RNaseH | ||
| Ligand | BDBM50183194 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_355438 (CHEMBL868998) | ||
| IC50 | 165±n/a nM | ||
| Citation |  Muraglia, E; Kinzel, OD; Laufer, R; Miller, MD; Moyer, G; Munshi, V; Orvieto, F; Palumbi, MC; Pescatore, G; Rowley, M; Williams, PD; Summa, V Tetrazole thioacetanilides: potent non-nucleoside inhibitors of WT HIV reverse transcriptase and its K103N mutant. Bioorg Med Chem Lett16:2748-52 (2006) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Reverse transcriptase/RNaseH | |||
| Name: | Reverse transcriptase/RNaseH | ||
| Synonyms: | HIV-1 Reverse Transcriptase RNase H | Human immunodeficiency virus type 1 reverse transcriptase | Reverse transcriptase/RNaseH | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 65229.15 | ||
| Organism: | Human immunodeficiency virus 1 | ||
| Description: | ChEMBL_1473730 | ||
| Residue: | 566 | ||
| Sequence: |
| ||
| BDBM50183194 | |||
| n/a | |||
| Name | BDBM50183194 | ||
| Synonyms: | 2-(1-mesityl-1H-tetrazol-5-ylthio)-N-(2-methyl-4-nitrophenyl)acetamide | CHEMBL377310 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C19H20N6O3S | ||
| Mol. Mass. | 412.465 | ||
| SMILES | Cc1cc(C)c(c(C)c1)-n1nnnc1SCC(=O)Nc1ccc(cc1C)[N+]([O-])=O |(-7.4,-3.06,;-7.06,-1.55,;-8.2,-.51,;-7.87,.99,;-9.01,2.03,;-6.4,1.46,;-5.26,.43,;-3.8,.9,;-5.59,-1.09,;-6.08,2.97,;-7.11,4.12,;-6.33,5.45,;-4.83,5.13,;-4.67,3.59,;-3.34,2.82,;-2,3.59,;-.67,2.82,;-.67,1.28,;.66,3.58,;2,2.81,;1.99,1.27,;3.32,.5,;4.66,1.27,;4.65,2.81,;3.32,3.58,;3.32,5.12,;5.99,.49,;5.99,-1.05,;7.33,1.26,)| | ||
| Structure | 
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