| Reaction Details |
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 | Report a problem with these data |
| Target | B1 bradykinin receptor |
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| Ligand | BDBM50184185 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_350972 (CHEMBL858907) |
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| Ki | 611±n/a nM |
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| Citation |  Kuduk, SD; Di Marco, CN; Chang, RK; Wood, MR; Kim, JJ; Schirripa, KM; Murphy, KL; Ransom, RW; Tang, C; Torrent, M; Ha, S; Prueksaritanont, T; Pettibone, DJ; Bock, MG 5-Piperazinyl pyridine carboxamide bradykinin B1 antagonists. Bioorg Med Chem Lett16:2791-5 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| B1 bradykinin receptor |
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| Name: | B1 bradykinin receptor |
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| Synonyms: | B1 BRADYKININ | B1 bradykinin receptor | B1R | BDKRB1 | BK-1 receptor | BKRB1_HUMAN | BRADYB1 | Bradykinin B1 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 40508.87 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P46663 |
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| Residue: | 353 |
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| Sequence: | MASSWPPLELQSSNQSQLFPQNATACDNAPEAWDLLHRVLPTFIISICFFGLLGNLFVLL
VFLLPRRQLNVAEIYLANLAASDLVFVLGLPFWAENIWNQFNWPFGALLCRVINGVIKAN
LFISIFLVVAISQDRYRVLVHPMASRRQQRRRQARVTCVLIWVVGGLLSIPTFLLRSIQA
VPDLNITACILLLPHEAWHFARIVELNILGFLLPLAAIVFFNYHILASLRTREEVSRTRC
GGRKDSKTTALILTLVVAFLVCWAPYHFFAFLEFLFQVQAVRGCFWEDFIDLGLQLANFF
AFTNSSLNPVIYVFVGRLFRTKVWELYKQCTPKSLAPISSSHRKEIFQLFWRN
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| BDBM50184185 |
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| n/a |
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| Name | BDBM50184185 |
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| Synonyms: | 3-chloro-3'-fluoro-4'-[(4-piperidin-1-ylmethyl-pyridin-2-ylamino)-methyl]-biphenyl-2-carboxylic acid methyl ester | CHEMBL377440 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H27ClFN3O2 |
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| Mol. Mass. | 467.963 |
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| SMILES | COC(=O)c1c(Cl)cccc1-c1ccc(CNc2cc(CN3CCCCC3)ccn2)c(F)c1 |
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| Structure | 
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