| Reaction Details |
|---|
 | Report a problem with these data |
| Target | DNA polymerase beta |
|---|
| Ligand | BDBM50184762 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_356788 (CHEMBL861141) |
|---|
| IC50 | 179000±n/a nM |
|---|
| Citation |  Doncaster, JR; Etchells, LL; Kershaw, NM; Nakamura, R; Ryan, H; Takeuchi, R; Sakaguchi, K; Sardarian, A; Whitehead, RC Synthetic analogues of the manzamenones and plakoridines which inhibit DNA polymerase. Bioorg Med Chem Lett16:2877-81 (2006) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| DNA polymerase beta |
|---|
| Name: | DNA polymerase beta |
|---|
| Synonyms: | DNA polymerase beta (Pol β) | DPOLB_HUMAN | POLB |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 38188.76 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 335 |
|---|
| Sequence: | MSKRKAPQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAK
KLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIK
TLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGS
FRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQ
LPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRP
LGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE
|
|
|
|---|
| BDBM50184762 |
|---|
| n/a |
|---|
| Name | BDBM50184762 |
|---|
| Synonyms: | CHEMBL210842 | plakevulin A |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H42O4 |
|---|
| Mol. Mass. | 382.5772 |
|---|
| SMILES | CCCCCCCCCCCCCCCC[C@]1(O)C=C[C@H](O)[C@H]1C(=O)OC |c:18| |
|---|
| Structure | 
|
|---|
Search and Browse
