| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2A |
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| Ligand | BDBM50185775 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_361713 (CHEMBL861444) |
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| Ki | 0.87±n/a nM |
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| Citation |  Ladduwahetty, T; Boase, AL; Mitchinson, A; Quin, C; Patel, S; Chapman, K; MacLeod, AM A new class of selective, non-basic 5-HT2A receptor antagonists. Bioorg Med Chem Lett16:3201-4 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 2A |
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| Name: | 5-hydroxytryptamine receptor 2A |
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| Synonyms: | 5-HT-2 | 5-HT-2A | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT-2A) | 5-hydroxytryptamine receptor 2A (5HT-2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_HUMAN | HTR2 | HTR2A | Serotonin receptor 2A |
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| Type: | undefined |
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| Mol. Mass.: | 52607.65 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P28223 |
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| Residue: | 471 |
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| Sequence: | MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGC
LSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIH
REPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGA
LLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYK
SSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV
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| BDBM50185775 |
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| n/a |
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| Name | BDBM50185775 |
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| Synonyms: | 7-(1-(2,4-difluorophenethyl)piperazine-4-carbonyl)-1H-indole-3-carbonitrile | CHEMBL207566 | EMD-281014 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H20F2N4O |
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| Mol. Mass. | 394.4172 |
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| SMILES | Fc1ccc(CCN2CCN(CC2)C(=O)c2cccc3c(c[nH]c23)C#N)c(F)c1 |
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| Structure | 
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