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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Long-chain fatty acid transport protein 4 | ||
| Ligand | BDBM50186041 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_372182 (CHEMBL870441) | ||
| IC50 | 150±n/a nM | ||
| Citation |  Blackburn, C; Guan, B; Brown, J; Cullis, C; Condon, SM; Jenkins, TJ; Peluso, S; Ye, Y; Gimeno, RE; Punreddy, S; Sun, Y; Wu, H; Hubbard, B; Kaushik, V; Tummino, P; Sanchetti, P; Yu Sun, D; Daniels, T; Tozzo, E; Balani, SK; Raman, P Identification and characterization of 4-aryl-3,4-dihydropyrimidin-2(1H)-ones as inhibitors of the fatty acid transporter FATP4. Bioorg Med Chem Lett16:3504-9 (2006) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Long-chain fatty acid transport protein 4 | |||
| Name: | Long-chain fatty acid transport protein 4 | ||
| Synonyms: | ACSVL4 | FATP4 | Fatty acid transport protein 4 | S27A4_HUMAN | SLC27A4 | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 72079.54 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | ChEMBL_372182 | ||
| Residue: | 643 | ||
| Sequence: |
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| BDBM50186041 | |||
| n/a | |||
| Name | BDBM50186041 | ||
| Synonyms: | (trans)-4-ethylcyclohexyl 6-methyl-4-(4-nitrophenyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate | CHEMBL211612 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H25N3O5 | ||
| Mol. Mass. | 387.4296 | ||
| SMILES | CC[C@H]1CC[C@@H](CC1)OC(=O)C1C(NC(=O)N=C1C)c1ccc(cc1)[N+]([O-])=O |wU:2.1,wD:5.8,c:17,(12.61,-3.74,;11.28,-2.97,;9.95,-3.72,;9.93,-5.26,;8.6,-6.02,;7.28,-5.24,;7.28,-3.71,;8.62,-2.95,;5.95,-6,;4.62,-5.23,;4.62,-3.68,;3.27,-6,;1.93,-5.23,;.6,-5.99,;.6,-7.54,;-.74,-8.34,;1.93,-8.3,;3.26,-7.55,;4.58,-8.36,;1.94,-3.67,;3.27,-2.9,;3.26,-1.35,;1.94,-.59,;.61,-1.36,;.62,-2.91,;1.94,.94,;3.27,1.71,;.61,1.72,)| | ||
| Structure | 
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