| Reaction Details |
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 | Report a problem with these data |
| Target | Sphingosine 1-phosphate receptor 4 |
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| Ligand | BDBM50186927 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_376409 (CHEMBL866637) |
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| EC50 | >10000±n/a nM |
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| Citation |  Yan, L; Huo, P; Doherty, G; Toth, L; Hale, JJ; Mills, SG; Hajdu, R; Keohane, CA; Rosenbach, MJ; Milligan, JA; Shei, GJ; Chrebet, G; Bergstrom, J; Card, D; Quackenbush, E; Wickham, A; Mandala, SM Discovery of 3-arylpropionic acids as potent agonists of sphingosine-1-phosphate receptor-1 (S1P1) with high selectivity against all other known S1P receptor subtypes. Bioorg Med Chem Lett16:3679-83 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sphingosine 1-phosphate receptor 4 |
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| Name: | Sphingosine 1-phosphate receptor 4 |
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| Synonyms: | EDG6 | Endothelial differentiation G-protein coupled receptor 6 | S1P receptor 4 | S1P receptor Edg-6 | S1P4 | S1PR4 | S1PR4_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-6 | Sphingosine-1-phosphate receptor 4 | sphingosine-1-phosphate 4 S1P4 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 41647.39 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 384 |
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| Sequence: | MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLV
VLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFL
REGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLP
LLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRP
AARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNS
AVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDS
FRGSRSLSFRMREPLSSISSVRSI
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| BDBM50186927 |
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| n/a |
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| Name | BDBM50186927 |
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| Synonyms: | 5-(4-cyclohexylphenyl)-3-o-tolyl-1,2,4-oxadiazole | CHEMBL208786 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H22N2O |
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| Mol. Mass. | 318.4122 |
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| SMILES | Cc1ccccc1-c1noc(n1)-c1ccc(cc1)C1CCCCC1 |
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| Structure | 
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