Reaction Details |
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Target | Galanin receptor type 3 |
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Ligand | BDBM50187918 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_384498 (CHEMBL866716) |
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Ki | 34±n/a nM |
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Citation | Konkel, MJ; Packiarajan, M; Chen, H; Topiwala, UP; Jimenez, H; Talisman, IJ; Coate, H; Walker, MW Amino substituted analogs of 1-phenyl-3-phenylimino-2-indolones with potent galanin Gal3 receptor binding affinity and improved solubility. Bioorg Med Chem Lett16:3950-4 (2006) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Galanin receptor type 3 |
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Name: | Galanin receptor type 3 |
Synonyms: | GALNR3 | GALR3 | GALR3_HUMAN | Galanin R3 | Galanin receptor 3 | Galanin receptor type 3 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 39599.97 |
Organism: | Homo sapiens (Human) |
Description: | Galanin R3 GALR3 HUMAN::O60755 |
Residue: | 368 |
Sequence: | MADAQNISLDSPGSVGAVAVPVVFALIFLLGTVGNGLVLAVLLQPGPSAWQEPGSTTDLF
ILNLAVADLCFILCCVPFQATIYTLDAWLFGALVCKAVHLLIYLTMYASSFTLAAVSVDR
YLAVRHPLRSRALRTPRNARAAVGLVWLLAALFSAPYLSYYGTVRYGALELCVPAWEDAR
RRALDVATFAAGYLLPVAVVSLAYGRTLRFLWAAVGPAGAAAAEARRRATGRAGRAMLAV
AALYALCWGPHHALILCFWYGRFAFSPATYACRLASHCLAYANSCLNPLVYALASRHFRA
RFRRLWPCGRRRRHRARRALRRVRPASSGPPGCPGDARPSGRLLAGGGQGPEPREGPVHG
GEAARGPE
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BDBM50187918 |
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n/a |
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Name | BDBM50187918 |
Synonyms: | 1-(4-(3-(diethylamino)propoxy)phenyl)-3-(3-(trifluoromethyl)phenylimino)indolin-2-one | CHEMBL213893 |
Type | Small organic molecule |
Emp. Form. | C28H28F3N3O2 |
Mol. Mass. | 495.536 |
SMILES | CCN(CC)CCCOc1ccc(cc1)N1C(=O)\C(=N\c2cccc(c2)C(F)(F)F)c2ccccc12 |
Structure |
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