| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2C |
|---|
| Ligand | BDBM50188139 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_384996 (CHEMBL869818) |
|---|
| Ki | 14±n/a nM |
|---|
| Citation |  Huck, BR; Llamas, L; Robarge, MJ; Dent, TC; Song, J; Hodnick, WF; Crumrine, C; Stricker-Krongrad, A; Harrington, J; Brunden, KR; Bennani, YL The design and synthesis of a tricyclic single-nitrogen scaffold that serves as a 5-HT2C receptor agonist. Bioorg Med Chem Lett16:4130-4 (2006) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 5-hydroxytryptamine receptor 2C |
|---|
| Name: | 5-hydroxytryptamine receptor 2C |
|---|
| Synonyms: | 5-HT-2C | 5-HT2C | 5-HT2C-INI | 5-HT2c VGI | 5-HTR2C | 5-hydroxytryptamine receptor 1C | 5-hydroxytryptamine receptor 2C (5-HT-2C) | 5-hydroxytryptamine receptor 2C (5HT-2C) | 5HT-1C | 5HT2C_HUMAN | HTR1C | HTR2C | Serotonin (5-HT3) receptor | Serotonin 2c (5-HT2c) receptor | Serotonin Receptor 2C |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 51836.79 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P28335 |
|---|
| Residue: | 458 |
|---|
| Sequence: | MVNLRNAVHSFLVHLIGLLVWQCDISVSPVAAIVTDIFNTSDGGRFKFPDGVQNWPALSI
VIIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVW
PLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWA
ISIGVSVPIPVIGLRDEEKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIYV
LRRQALMLLHGHTEEPPGLSLDFLKCCKRNTAEEENSANPNQDQNARRRKKKERRPRGTM
QAINNERKASKVLGIVFFVFLIMWCPFFITNILSVLCEKSCNQKLMEKLLNVFVWIGYVC
SGINPLVYTLFNKIYRRAFSNYLRCNYKVEKKPPVRQIPRVAATALSGRELNVNIYRHTN
EPVIEKASDNEPGIEMQVENLELPVNPSSVVSERISSV
|
|
|
|---|
| BDBM50188139 |
|---|
| n/a |
|---|
| Name | BDBM50188139 |
|---|
| Synonyms: | (3aS,8R,8aS)-6-chloro-5-methoxy-8-methyl-1,2,3,3a,8,8a-hexahydro-indeno[1,2-c]pyrrole | CHEMBL425777 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H16ClNO |
|---|
| Mol. Mass. | 237.725 |
|---|
| SMILES | COc1cc2[C@H]3CNC[C@H]3[C@@H](C)c2cc1Cl |
|---|
| Structure | 
|
|---|
Search and Browse
