| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM50188208 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_379863 (CHEMBL864851) |
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| IC50 | 18589±n/a nM |
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| Citation |  Nefzi, A; Ostresh, JM; Appel, JR; Bidlack, J; Dooley, CT; Houghten, RA Identification of potent and highly selective chiral tri-amine and tetra-amine mu opioid receptors ligands: an example of lead optimization using mixture-based libraries. Bioorg Med Chem Lett16:4331-8 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 11165.58 |
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| Organism: | GUINEA PIG |
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| Description: | P97266 |
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| Residue: | 98 |
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| Sequence: | YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSI
FTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
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| BDBM50188208 |
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| n/a |
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| Name | BDBM50188208 |
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| Synonyms: | 4-[(2S)-2-amino-3-{[(2S)-1-(4-hydroxyphenyl)-3-[(naphthalen-2-ylmethyl)[(2S)-1-[(2S)-2-{[(naphthalen-2-ylmethyl)amino]methyl}pyrrolidin-1-yl]-3-phenylpropan-2-yl]amino]propan-2-yl](naphthalen-2-ylmethyl)amino}propyl]phenol | CHEMBL269502 |
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| Type | Small organic molecule |
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| Emp. Form. | C65H69N5O2 |
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| Mol. Mass. | 952.2757 |
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| SMILES | N[C@H](CN(Cc1ccc2ccccc2c1)[C@H](CN(Cc1ccc2ccccc2c1)[C@H](CN1CCC[C@H]1CNCc1ccc2ccccc2c1)Cc1ccccc1)Cc1ccc(O)cc1)Cc1ccc(O)cc1 |
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| Structure | 
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