Ki Summary new BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetMelatonin receptor
LigandBDBM50188405
Substrate/Competitorn/a
Meas. Tech.ChEMBL_362909
Ki 307±n/a nM
Citation Tsotinis AVlachou MPapahatjis DPCalogeropoulou TNikas SPGarratt PJPiccio VVonhoff SDavidson KTeh MTSugden D Mapping the melatonin receptor. 7. Subtype selective ligands based on beta-substituted N-acyl-5-methoxytryptamines and beta-substituted N-acyl-5-methoxy-1-methyltryptamines. J Med Chem 49:3509-19 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Melatonin receptor
Name:Melatonin receptor
Synonyms:MTNR1A | MTNR1A protein | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A
Type:Enzyme
Mol. Mass.:39392.94
Organism:Homo sapiens (Human)
Description:P48039
Residue:350
Sequence:
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRN
AGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITG
IAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFA
QSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM
FVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQ
NFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50188405
n/a
NameBDBM50188405
Synonyms:CHEMBL382579 | N-(2-[5-methoxy-1-methyl-1H-indol-3-yl]-2,2-trimethyleneethyl)cyclopropanecarboxamide
TypeSmall organic molecule
Emp. Form.C19H24N2O2
Mol. Mass.312.4061
SMILESCOc1ccc2n(C)cc(c2c1)C1(CNC(=O)C2CC2)CCC1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: