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TargetMelatonin receptor
LigandBDBM50188394
Substrate/Competitorn/a
Meas. Tech.ChEMBL_362910
Ki 0.41±n/a nM
Citation Tsotinis AVlachou MPapahatjis DPCalogeropoulou TNikas SPGarratt PJPiccio VVonhoff SDavidson KTeh MTSugden D Mapping the melatonin receptor. 7. Subtype selective ligands based on beta-substituted N-acyl-5-methoxytryptamines and beta-substituted N-acyl-5-methoxy-1-methyltryptamines. J Med Chem 49:3509-19 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Melatonin receptor
Name:Melatonin receptor
Synonyms:MTNR1B | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2)
Type:Enzyme
Mol. Mass.:40203.54
Organism:Homo sapiens (Human)
Description:P49286
Residue:362
Sequence:
MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLL
VILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVM
GLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGS
LEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRL
CLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFN
SCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQAD
AL
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  Blast E-value cutoff:
BDBM50188394
n/a
NameBDBM50188394
Synonyms:(+)-N-(2-[5-methoxy-1-methyl-1H-indol-3-yl]propyl)acetamide | CHEMBL210791 | N-(2-[5-methoxy-1-methyl-1H-indol-3-yl]propyl)acetamide
TypeSmall organic molecule
Emp. Form.C15H20N2O2
Mol. Mass.260.3315
SMILESCOc1ccc2n(C)cc(C(C)CNC(C)=O)c2c1
Structure
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