Ki Summary new BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetMelatonin receptor
LigandBDBM50188410
Substrate/Competitorn/a
Meas. Tech.ChEMBL_362909
Ki 86±n/a nM
Citation Tsotinis AVlachou MPapahatjis DPCalogeropoulou TNikas SPGarratt PJPiccio VVonhoff SDavidson KTeh MTSugden D Mapping the melatonin receptor. 7. Subtype selective ligands based on beta-substituted N-acyl-5-methoxytryptamines and beta-substituted N-acyl-5-methoxy-1-methyltryptamines. J Med Chem 49:3509-19 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Melatonin receptor
Name:Melatonin receptor
Synonyms:MTNR1A | MTNR1A protein | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A
Type:Enzyme
Mol. Mass.:39392.94
Organism:Homo sapiens (Human)
Description:P48039
Residue:350
Sequence:
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRN
AGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITG
IAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFA
QSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM
FVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQ
NFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50188410
n/a
NameBDBM50188410
Synonyms:CHEMBL377871 | N-(2-[5-methoxy-1-methyl-1H-indol-3-yl]-2,2-dimethyleneethyl)propanamide
TypeSmall organic molecule
Emp. Form.C17H22N2O2
Mol. Mass.286.3688
SMILESCCC(=O)NCC1(CC1)c1cn(C)c2ccc(OC)cc12
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: