| Reaction Details |
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 | Report a problem with these data |
| Target | Melatonin receptor |
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| Ligand | BDBM50188423 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_362910 |
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| Ki | 2.75±n/a nM |
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| Citation |  Tsotinis A; Vlachou M; Papahatjis DP; Calogeropoulou T; Nikas SP; Garratt PJ; Piccio V; Vonhoff S; Davidson K; Teh MT; Sugden D Mapping the melatonin receptor. 7. Subtype selective ligands based on beta-substituted N-acyl-5-methoxytryptamines and beta-substituted N-acyl-5-methoxy-1-methyltryptamines. J Med Chem 49:3509-19 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melatonin receptor |
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| Name: | Melatonin receptor |
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| Synonyms: | MTNR1B | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2) |
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| Type: | Enzyme |
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| Mol. Mass.: | 40203.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P49286 |
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| Residue: | 362 |
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| Sequence: | MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLL
VILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVM
GLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGS
LEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRL
CLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFN
SCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQAD
AL
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| BDBM50188423 |
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| n/a |
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| Name | BDBM50188423 |
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| Synonyms: | CHEMBL206472 | beta,beta-dimethylmelatonin |
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| Type | Small organic molecule |
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| Emp. Form. | C15H20N2O2 |
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| Mol. Mass. | 260.3315 |
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| SMILES | COc1ccc2[nH]cc(c2c1)C(C)(C)CNC(C)=O |
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| Structure | 
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