| Reaction Details |
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 | Report a problem with these data |
| Target | Melatonin receptor |
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| Ligand | BDBM50188400 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_362909 |
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| Ki | 8.2±n/a nM |
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| Citation |  Tsotinis A; Vlachou M; Papahatjis DP; Calogeropoulou T; Nikas SP; Garratt PJ; Piccio V; Vonhoff S; Davidson K; Teh MT; Sugden D Mapping the melatonin receptor. 7. Subtype selective ligands based on beta-substituted N-acyl-5-methoxytryptamines and beta-substituted N-acyl-5-methoxy-1-methyltryptamines. J Med Chem 49:3509-19 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melatonin receptor |
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| Name: | Melatonin receptor |
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| Synonyms: | MTNR1A | MTNR1A protein | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A |
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| Type: | Enzyme |
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| Mol. Mass.: | 39392.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P48039 |
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| Residue: | 350 |
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| Sequence: | MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRN
AGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITG
IAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFA
QSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM
FVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQ
NFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
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| BDBM50188400 |
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| n/a |
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| Name | BDBM50188400 |
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| Synonyms: | CHEMBL207960 | N-(2-[5-methoxy-1H-indol-3-yl]-2,2-trimethyleneethyl)acetamide |
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| Type | Small organic molecule |
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| Emp. Form. | C16H20N2O2 |
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| Mol. Mass. | 272.3422 |
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| SMILES | COc1ccc2[nH]cc(c2c1)C1(CNC(C)=O)CCC1 |
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| Structure | 
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