Reaction Details |
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Target | Galanin receptor type 3 |
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Ligand | BDBM50189601 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_368823 (CHEMBL864918) |
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Ki | >10000±n/a nM |
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Citation | Konkel, MJ; Lagu, B; Boteju, LW; Jimenez, H; Noble, S; Walker, MW; Chandrasena, G; Blackburn, TP; Nikam, SS; Wright, JL; Kornberg, BE; Gregory, T; Pugsley, TA; Akunne, H; Zoski, K; Wise, LD 3-arylimino-2-indolones are potent and selective galanin GAL3 receptor antagonists. J Med Chem49:3757-8 (2006) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Galanin receptor type 3 |
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Name: | Galanin receptor type 3 |
Synonyms: | GALNR3 | GALR3 | GALR3_HUMAN | Galanin R3 | Galanin receptor 3 | Galanin receptor type 3 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 39599.97 |
Organism: | Homo sapiens (Human) |
Description: | Galanin R3 GALR3 HUMAN::O60755 |
Residue: | 368 |
Sequence: | MADAQNISLDSPGSVGAVAVPVVFALIFLLGTVGNGLVLAVLLQPGPSAWQEPGSTTDLF
ILNLAVADLCFILCCVPFQATIYTLDAWLFGALVCKAVHLLIYLTMYASSFTLAAVSVDR
YLAVRHPLRSRALRTPRNARAAVGLVWLLAALFSAPYLSYYGTVRYGALELCVPAWEDAR
RRALDVATFAAGYLLPVAVVSLAYGRTLRFLWAAVGPAGAAAAEARRRATGRAGRAMLAV
AALYALCWGPHHALILCFWYGRFAFSPATYACRLASHCLAYANSCLNPLVYALASRHFRA
RFRRLWPCGRRRRHRARRALRRVRPASSGPPGCPGDARPSGRLLAGGGQGPEPREGPVHG
GEAARGPE
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BDBM50189601 |
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n/a |
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Name | BDBM50189601 |
Synonyms: | (E)-3-(4-methoxyphenylimino)indolin-2-one | (E/Z)-3-(4-methoxyphenylimino)indolin-2-one | CHEMBL378695 |
Type | Small organic molecule |
Emp. Form. | C15H12N2O2 |
Mol. Mass. | 252.268 |
SMILES | COc1ccc(cc1)\N=C1\C(=O)Nc2ccccc12 |
Structure |
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