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TargetD(2) dopamine receptor
LigandBDBM50190087
Substrate/Competitorn/a
Meas. Tech.ChEMBL_393314
Ki 8±n/a nM
Citation Su JTang HMcKittrick BABurnett DAZhang HSmith-Torhan AFawzi ALachowicz J Modification of the clozapine structure by parallel synthesis. Bioorg Med Chem Lett 16:4548-53 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
D(2) dopamine receptor
Name:Dopamine receptor D2L/neurotensin receptor NTS1
Synonyms:DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like
Type:Cell-surface receptors
Mol. Mass.:50647.10
Organism:Homo sapiens (Human)
Description:P14416
Residue:443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSR
RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA
VNPIIYTTFNIEFRKAFLKILHC
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  Blast E-value cutoff:
BDBM50190087
n/a
NameBDBM50190087
Synonyms:8-chloro-11-[4-(2,2-difluoro-benzo[1,3]dioxol-4-ylmethyl)-piperazin-1-yl]-5H-dibenzo[b,e][1,4]diazepine | CHEMBL384634
TypeSmall organic molecule
Emp. Form.C25H21ClF2N4O2
Mol. Mass.482.91
SMILESFC1(F)Oc2cccc(CN3CCN(CC3)C3=Nc4cc(Cl)ccc4Nc4ccccc34)c2O1 |t:17|
Structure
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