Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase
LigandBDBM50190558
Substrate/Competitorn/a
Meas. Tech.ChEMBL_373621 (CHEMBL869761)
Ki 2300±n/a nM
Citation Nguyen, CRuda, GFSchipani, AKasinathan, GLeal, IMusso-Buendia, AKaiser, MBrun, RRuiz-Pérez, LMSahlberg, BLJohansson, NGGonzalez-Pacanowska, DGilbert, IH Acyclic nucleoside analogues as inhibitors of Plasmodium falciparum dUTPase. J Med Chem49:4183-95 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Deoxyuridine 5'-triphosphate nucleotidohydrolase
Name:Deoxyuridine 5'-triphosphate nucleotidohydrolase
Synonyms:dUTP pyrophosphatase
Type:Protein
Mol. Mass.:19574.43
Organism:Plasmodium falciparum
Description:Q8II92
Residue:173
Sequence:
MHLKIVCLSDEVREMYKNHKTHHEGDSGLDLFIVKDEVLKPKSTTFVKLGIKAIALQYKS
NYYYKCEKSENKKKDDDKSNIVNTSFLLFPRSSISKTPLRLANSIGLIDAGYRGEIIAAL
DNTSDQEYHIKKNDKLVQLVSFTGEPLSFELVEELDETSRGEGGFGSTSNNKY
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50190558
n/a
NameBDBM50190558
Synonyms:1-(6-trityloxyhexyl)uracil | CHEMBL378414
TypeSmall organic molecule
Emp. Form.C29H30N2O3
Mol. Mass.454.5601
SMILESO=c1ccn(CCCCCCOC(c2ccccc2)(c2ccccc2)c2ccccc2)c(=O)[nH]1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: