| Reaction Details |
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 | Report a problem with these data |
| Target | Deoxyuridine 5'-triphosphate nucleotidohydrolase |
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| Ligand | BDBM50190567 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_373621 (CHEMBL869761) |
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| Ki | 2200±n/a nM |
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| Citation |  Nguyen, C; Ruda, GF; Schipani, A; Kasinathan, G; Leal, I; Musso-Buendia, A; Kaiser, M; Brun, R; Ruiz-Pérez, LM; Sahlberg, BL; Johansson, NG; Gonzalez-Pacanowska, D; Gilbert, IH Acyclic nucleoside analogues as inhibitors of Plasmodium falciparum dUTPase. J Med Chem49:4183-95 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Deoxyuridine 5'-triphosphate nucleotidohydrolase |
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| Name: | Deoxyuridine 5'-triphosphate nucleotidohydrolase |
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| Synonyms: | dUTP pyrophosphatase |
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| Type: | Protein |
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| Mol. Mass.: | 19574.43 |
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| Organism: | Plasmodium falciparum |
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| Description: | Q8II92 |
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| Residue: | 173 |
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| Sequence: | MHLKIVCLSDEVREMYKNHKTHHEGDSGLDLFIVKDEVLKPKSTTFVKLGIKAIALQYKS
NYYYKCEKSENKKKDDDKSNIVNTSFLLFPRSSISKTPLRLANSIGLIDAGYRGEIIAAL
DNTSDQEYHIKKNDKLVQLVSFTGEPLSFELVEELDETSRGEGGFGSTSNNKY
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| BDBM50190567 |
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| n/a |
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| Name | BDBM50190567 |
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| Synonyms: | 1-(4-triphenylsilyloxybutyl)uracil | CHEMBL387177 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H26N2O3Si |
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| Mol. Mass. | 442.5817 |
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| SMILES | O=c1ccn(CCCCO[Si](c2ccccc2)(c2ccccc2)c2ccccc2)c(=O)[nH]1 |
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| Structure | 
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