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TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial
LigandBDBM50190562
Substrate/Competitorn/a
Meas. Tech.ChEMBL_373622 (CHEMBL869762)
Ki 383000±n/a nM
Citation Nguyen, CRuda, GFSchipani, AKasinathan, GLeal, IMusso-Buendia, AKaiser, MBrun, RRuiz-Pérez, LMSahlberg, BLJohansson, NGGonzalez-Pacanowska, DGilbert, IH Acyclic nucleoside analogues as inhibitors of Plasmodium falciparum dUTPase. J Med Chem49:4183-95 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial
Name:Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial
Synonyms:DUT | DUT_HUMAN | Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) | Deoxyuridine triphosphatase (dUTPase) | dUTP pyrophosphatase
Type:Enzyme
Mol. Mass.:26574.03
Organism:Homo sapiens (Human)
Description:P33316
Residue:252
Sequence:
MTPLCPRPALCYHFLTSLLRSAMQNARGARQRAEAAVLSGPGPPLGRAAQHGIPRPLSSA
GRLSQGCRGASTVGAAGWKGELPKAGGSPAPGPETPAISPSKRARPAEVGGMQLRFARLS
EHATAPTRGSARAAGYDLYSAYDYTIPPMEKAVVKTDIQIALPSGCYGRVAPRSGLAAKH
FIDVGAGVIDEDYRGNVGVVLFNFGKEKFEVKKGDRIAQLICERIFYPEIEEVQALDDTE
RGSGGFGSTGKN
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BDBM50190562
n/a
NameBDBM50190562
Synonyms:1-(6-triphenylsilyloxyhexyl)uracil | CHEMBL212690
TypeSmall organic molecule
Emp. Form.C28H30N2O3Si
Mol. Mass.470.6349
SMILESO=c1ccn(CCCCCCO[Si](c2ccccc2)(c2ccccc2)c2ccccc2)c(=O)[nH]1
Structure
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