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TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase)
LigandBDBM50190532
Substrate/Competitorn/a
Meas. Tech.ChEMBL_373622
Ki 21000±n/a nM
Citation Nguyen CRuda GFSchipani AKasinathan GLeal IMusso-Buendia AKaiser MBrun RRuiz-Pérez LMSahlberg BLJohansson NGGonzalez-Pacanowska DGilbert IH Acyclic nucleoside analogues as inhibitors of Plasmodium falciparum dUTPase. J Med Chem 49:4183-95 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase)
Name:Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase)
Synonyms:Deoxyuridine triphosphatase (dUTPase) | dUTP pyrophosphatase
Type:Enzyme
Mol. Mass.:26574.03
Organism:Homo sapiens (Human)
Description:P33316
Residue:252
Sequence:
MTPLCPRPALCYHFLTSLLRSAMQNARGARQRAEAAVLSGPGPPLGRAAQHGIPRPLSSA
GRLSQGCRGASTVGAAGWKGELPKAGGSPAPGPETPAISPSKRARPAEVGGMQLRFARLS
EHATAPTRGSARAAGYDLYSAYDYTIPPMEKAVVKTDIQIALPSGCYGRVAPRSGLAAKH
FIDVGAGVIDEDYRGNVGVVLFNFGKEKFEVKKGDRIAQLICERIFYPEIEEVQALDDTE
RGSGGFGSTGKN
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  Blast E-value cutoff:
BDBM50190532
n/a
NameBDBM50190532
Synonyms:1-[4-hydroxy-2-(trityloxymethyl)butyl]uracil | CHEMBL213863
TypeSmall organic molecule
Emp. Form.C28H28N2O4
Mol. Mass.456.5329
SMILESOCCC(COC(c1ccccc1)(c1ccccc1)c1ccccc1)Cn1ccc(=O)[nH]c1=O
Structure
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