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TargetdUTP pyrophosphatase
LigandBDBM50190532
Substrate/Competitorn/a
Meas. Tech.ChEMBL_373621
Ki 900±n/a nM
Citation Nguyen CRuda GFSchipani AKasinathan GLeal IMusso-Buendia AKaiser MBrun RRuiz-Pérez LMSahlberg BLJohansson NGGonzalez-Pacanowska DGilbert IH Acyclic nucleoside analogues as inhibitors of Plasmodium falciparum dUTPase. J Med Chem 49:4183-95 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
dUTP pyrophosphatase
Name:dUTP pyrophosphatase
Synonyms:Putative deoxyuridine 5''-triphosphate nucleotidohydrolase
Type:Protein
Mol. Mass.:19574.43
Organism:Plasmodium falciparum
Description:Q8II92
Residue:173
Sequence:
MHLKIVCLSDEVREMYKNHKTHHEGDSGLDLFIVKDEVLKPKSTTFVKLGIKAIALQYKS
NYYYKCEKSENKKKDDDKSNIVNTSFLLFPRSSISKTPLRLANSIGLIDAGYRGEIIAAL
DNTSDQEYHIKKNDKLVQLVSFTGEPLSFELVEELDETSRGEGGFGSTSNNKY
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BDBM50190532
n/a
NameBDBM50190532
Synonyms:1-[4-hydroxy-2-(trityloxymethyl)butyl]uracil | CHEMBL213863
TypeSmall organic molecule
Emp. Form.C28H28N2O4
Mol. Mass.456.5329
SMILESOCCC(COC(c1ccccc1)(c1ccccc1)c1ccccc1)Cn1ccc(=O)[nH]c1=O
Structure
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