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TargetdUTP pyrophosphatase
LigandBDBM50190555
Substrate/Competitorn/a
Meas. Tech.ChEMBL_373621
Ki 900±n/a nM
Citation Nguyen CRuda GFSchipani AKasinathan GLeal IMusso-Buendia AKaiser MBrun RRuiz-Pérez LMSahlberg BLJohansson NGGonzalez-Pacanowska DGilbert IH Acyclic nucleoside analogues as inhibitors of Plasmodium falciparum dUTPase. J Med Chem 49:4183-95 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
dUTP pyrophosphatase
Name:dUTP pyrophosphatase
Synonyms:Putative deoxyuridine 5''-triphosphate nucleotidohydrolase
Type:Protein
Mol. Mass.:19574.43
Organism:Plasmodium falciparum
Description:Q8II92
Residue:173
Sequence:
MHLKIVCLSDEVREMYKNHKTHHEGDSGLDLFIVKDEVLKPKSTTFVKLGIKAIALQYKS
NYYYKCEKSENKKKDDDKSNIVNTSFLLFPRSSISKTPLRLANSIGLIDAGYRGEIIAAL
DNTSDQEYHIKKNDKLVQLVSFTGEPLSFELVEELDETSRGEGGFGSTSNNKY
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  Blast E-value cutoff:
BDBM50190555
n/a
NameBDBM50190555
Synonyms:1-(4-tritylaminobutyl)uracil | CHEMBL211181
TypeSmall organic molecule
Emp. Form.C27H27N3O2
Mol. Mass.425.5222
SMILESO=c1ccn(CCCCNC(c2ccccc2)(c2ccccc2)c2ccccc2)c(=O)[nH]1
Structure
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