| Reaction Details |
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 | Report a problem with these data |
| Target | Melanin-concentrating hormone receptor 1 |
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| Ligand | BDBM50192518 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_391846 (CHEMBL862441) |
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| Ki | 14±n/a nM |
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| Citation |  Ma, V; Bannon, AW; Baumgartner, J; Hale, C; Hsieh, F; Hulme, C; Rorrer, K; Salon, J; van Staden, C; Tempest, P Solid-phase synthesis and structure-activity relationships of novel biarylethers as melanin-concentrating hormone receptor-1 antagonists. Bioorg Med Chem Lett16:5066-72 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melanin-concentrating hormone receptor 1 |
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| Name: | Melanin-concentrating hormone receptor 1 |
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| Synonyms: | Gpr24 | MCHR1_MOUSE | Mchr1 | Slc1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 39133.74 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_818502 |
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| Residue: | 353 |
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| Sequence: | MDLQASLLSTGPNASNISDGQDNFTLAGPPPRTRSVSYINIIMPSVFGTICLLGIVGNST
VIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLIT
AMDANSQFTSTYILTAMAIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWL
YARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVA
PASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLG
YANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT
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| BDBM50192518 |
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| n/a |
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| Name | BDBM50192518 |
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| Synonyms: | 1-(2-(3,4-dimethylphenoxy)-5-((2-(pyrrolidin-1-yl)ethyl)carbamoyl)phenyl)-3-phenylurea | CHEMBL216192 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H32N4O3 |
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| Mol. Mass. | 472.5787 |
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| SMILES | Cc1ccc(Oc2ccc(cc2NC(=O)Nc2ccccc2)C(=O)NCCN2CCCC2)cc1C |
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| Structure | 
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