| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 6 |
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| Ligand | BDBM50193471 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_383814 (CHEMBL854532) |
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| Ki | 15±n/a nM |
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| Citation |  Sikazwe, D; Bondarev, ML; Dukat, M; Rangisetty, JB; Roth, BL; Glennon, RA Binding of sulfonyl-containing arylalkylamines at human 5-HT6 serotonin receptors. J Med Chem49:5217-25 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 6 |
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| Name: | 5-hydroxytryptamine receptor 6 |
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| Synonyms: | 5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 (5-HT-6) | 5-hydroxytryptamine receptor 6 (5-HT6R) | 5-hydroxytryptamine receptor 6 (5HT6) | 5HT6R_HUMAN | HTR6 | Serotonin (5-HT3) receptor | Serotonin 6 (5-HT6) receptor | Serotonin Receptor 6 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 46968.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P50406 |
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| Residue: | 440 |
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| Sequence: | MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNT
SNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLI
SLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQC
RLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVP
RTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPG
LFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGP
RPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNF
FNIDPAEPELRPHPLGIPTN
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| BDBM50193471 |
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| n/a |
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| Name | BDBM50193471 |
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| Synonyms: | CHEMBL378892 | N,N-dimethyl-2-(1-(phenylsulfonyl)-1H-pyrrol-3-yl)ethanamine | N,N-dimethyl-2-[1-(benzenesulfonyl)-1H-pyrrol-3-yl]-1-aminoethane |
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| Type | Small organic molecule |
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| Emp. Form. | C14H18N2O2S |
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| Mol. Mass. | 278.37 |
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| SMILES | CN(C)CCc1ccn(c1)S(=O)(=O)c1ccccc1 |
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| Structure | 
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