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TargetDelta-type opioid receptor
LigandBDBM50194235
Substrate/Competitorn/a
Meas. Tech.ChEMBL_392436 (CHEMBL913211)
IC50 0.400000±n/a nM
Citation Thomas, JBZhang, LNavarro, HACarroll, FI Highly potent and selective phenylmorphan-based inverse agonists of the opioid delta receptor. J Med Chem49:5597-609 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Delta-type opioid receptor
Name:Delta-type opioid receptor
Synonyms:D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:40382.98
Organism:Homo sapiens (Human)
Description:Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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  Blast E-value cutoff:
BDBM50194235
n/a
NameBDBM50194235
Synonyms:(+)-N-[(1S,4R,5R,7S)-5-(3-hydroxyphenyl)-4-methyl-2-(3-phenylpropyl)-2-azabicyclo[3.3.1]non-7-yl]-2-methyl-2-phenylpropanamide | CHEMBL387245
TypeSmall organic molecule
Emp. Form.C34H42N2O2
Mol. Mass.510.7095
SMILESC[C@H]1CN(CCCc2ccccc2)[C@@H]2C[C@H](C[C@]1(C2)c1cccc(O)c1)NC(=O)C(C)(C)c1ccccc1
Structure
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