| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Coagulation factor X |
|---|
| Ligand | BDBM50194744 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_398433 (CHEMBL908012) |
|---|
| IC50 | 96000±n/a nM |
|---|
| Citation |  Joossens, J; Van der Veken, P; Surpateanu, G; Lambeir, AM; El-Sayed, I; Ali, OM; Augustyns, K; Haemers, A Diphenyl phosphonate inhibitors for the urokinase-type plasminogen activator: optimization of the P4 position. J Med Chem49:5785-93 (2006) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Coagulation factor X |
|---|
| Name: | Coagulation factor X |
|---|
| Synonyms: | Coagulation factor X | F10 | FA10_BOVIN | Factor Xa (fXa) |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 54498.45 |
|---|
| Organism: | Bos taurus |
|---|
| Description: | ChEMBL_1364435 |
|---|
| Residue: | 492 |
|---|
| Sequence: | MAGLLHLVLLSTALGGLLRPAGSVFLPRDQAHRVLQRARRANSFLEEVKQGNLERECLEE
ACSLEEAREVFEDAEQTDEFWSKYKDGDQCEGHPCLNQGHCKDGIGDYTCTCAEGFEGKN
CEFSTREICSLDNGGCDQFCREERSEVRCSCAHGYVLGDDSKSCVSTERFPCGKFTQGRS
RRWAIHTSEDALDASELEHYDPADLSPTESSLDLLGLNRTEPSAGEDGSQVVRIVGGRDC
AEGECPWQALLVNEENEGFCGGTILNEFYVLTAAHCLHQAKRFTVRVGDRNTEQEEGNEM
AHEVEMTVKHSRFVKETYDFDIAVLRLKTPIRFRRNVAPACLPEKDWAEATLMTQKTGIV
SGFGRTHEKGRLSSTLKMLEVPYVDRSTCKLSSSFTITPNMFCAGYDTQPEDACQGDSGG
PHVTRFKDTYFVTGIVSWGEGCARKGKFGVYTKVSNFLKWIDKIMKARAGAAGSRGHSEA
PATWTVPPPLPL
|
|
|
|---|
| BDBM50194744 |
|---|
| n/a |
|---|
| Name | BDBM50194744 |
|---|
| Synonyms: | CHEMBL385897 | diphenyl 1-[(N-naphthalenesulfonyl-D-seryl)-L-alanyl]amino-2-(4-guanidinophenyl)ethanephosphonate |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C37H39N6O8PS |
|---|
| Mol. Mass. | 758.78 |
|---|
| SMILES | [#6]-[#6@H](-[#7]-[#6](=O)-[#6@@H](-[#6]-[#8])-[#7]S(=O)(=O)c1cccc2ccccc12)-[#6](=O)-[#7]-[#6](-[#6]-c1ccc(cc1)\[#7]=[#6](\[#7])-[#7])P(=O)([#8]-c1ccccc1)[#8]-c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
