| Reaction Details |
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 | Report a problem with these data |
| Target | Histone deacetylase 2b |
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| Ligand | BDBM50195600 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_416717 (CHEMBL909983) |
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| IC50 | 80±n/a nM |
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| Citation |  Mai, A; Massa, S; Rotili, D; Simeoni, S; Ragno, R; Botta, G; Nebbioso, A; Miceli, M; Altucci, L; Brosch, G Synthesis and biological properties of novel, uracil-containing histone deacetylase inhibitors. J Med Chem49:6046-56 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone deacetylase 2b |
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| Name: | Histone deacetylase 2b |
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| Synonyms: | Histone deacetylase HD2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 30785.07 |
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| Organism: | Zea mays |
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| Description: | ChEMBL_87549 |
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| Residue: | 286 |
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| Sequence: | MEVGGQEVKPGATVSCKVGDGLVIHLSQAALGESKKASENAILSVNIDDKKLVLGTLSVE
KHPQISCDLVFDKDFELPHNSKTRSVFFRGYKSPVPLFESNSGEDSSDEELKTDQIPLQN
NEIKISAAKVPAKDDDDDVFIILAMMMMIYSSDDDDDDFTTSDSDNEMSEEDDSSDEDEM
SEEDDSSDEDEMSGGADPSDDSSDESGSEHTSAPKKTDVVVGKKRAIKAEAPYGKKAKSE
QSSQKTGDKASTSHPAKQSIKTPADKSRKTPTADKKSPKSGSHGCK
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| BDBM50195600 |
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| n/a |
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| Name | BDBM50195600 |
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| Synonyms: | CHEMBL216850 | N-hydroxy-4-(3,4-dihydro-6-benzyl-4-oxopyrimidin-2-ylthio)methylcinnamylamide |
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| Type | Small organic molecule |
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| Emp. Form. | C21H19N3O3S |
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| Mol. Mass. | 393.459 |
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| SMILES | ONC(=O)C=Cc1ccc(CSc2nc(Cc3ccccc3)cc(=O)[nH]2)cc1 |w:5.5| |
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| Structure | 
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