| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Histone deacetylase 2b |
|---|
| Ligand | BDBM50195605 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_416717 (CHEMBL909983) |
|---|
| IC50 | 17±n/a nM |
|---|
| Citation |  Mai, A; Massa, S; Rotili, D; Simeoni, S; Ragno, R; Botta, G; Nebbioso, A; Miceli, M; Altucci, L; Brosch, G Synthesis and biological properties of novel, uracil-containing histone deacetylase inhibitors. J Med Chem49:6046-56 (2006) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Histone deacetylase 2b |
|---|
| Name: | Histone deacetylase 2b |
|---|
| Synonyms: | Histone deacetylase HD2 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 30785.07 |
|---|
| Organism: | Zea mays |
|---|
| Description: | ChEMBL_87549 |
|---|
| Residue: | 286 |
|---|
| Sequence: | MEVGGQEVKPGATVSCKVGDGLVIHLSQAALGESKKASENAILSVNIDDKKLVLGTLSVE
KHPQISCDLVFDKDFELPHNSKTRSVFFRGYKSPVPLFESNSGEDSSDEELKTDQIPLQN
NEIKISAAKVPAKDDDDDVFIILAMMMMIYSSDDDDDDFTTSDSDNEMSEEDDSSDEDEM
SEEDDSSDEDEMSGGADPSDDSSDESGSEHTSAPKKTDVVVGKKRAIKAEAPYGKKAKSE
QSSQKTGDKASTSHPAKQSIKTPADKSRKTPTADKKSPKSGSHGCK
|
|
|
|---|
| BDBM50195605 |
|---|
| n/a |
|---|
| Name | BDBM50195605 |
|---|
| Synonyms: | CHEMBL214533 | N-hydroxy-3-(3,4-dihydro-6-phenyl-4-oxopyrimidin-2-ylthio)methylcinnamylamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H17N3O3S |
|---|
| Mol. Mass. | 379.432 |
|---|
| SMILES | ONC(=O)C=Cc1cccc(CSc2nc(cc(=O)[nH]2)-c2ccccc2)c1 |w:5.5| |
|---|
| Structure | 
|
|---|
Search and Browse
