| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cycloartenol-C-24-methyltransferase |
|---|
| Ligand | BDBM50195621 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_415083 (CHEMBL912398) |
|---|
| IC50 | >100000±n/a nM |
|---|
| Citation |  Gros, L; Lorente, SO; Jimenez, CJ; Yardley, V; Rattray, L; Wharton, H; Little, S; Croft, SL; Ruiz-Perez, LM; Gonzalez-Pacanowska, D; Gilbert, IH Evaluation of azasterols as anti-parasitics. J Med Chem49:6094-103 (2006) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cycloartenol-C-24-methyltransferase |
|---|
| Name: | Cycloartenol-C-24-methyltransferase |
|---|
| Synonyms: | 24-sterol C-methyltransferase | CPH | SMT1 | SMT1_ARATH |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 38266.01 |
|---|
| Organism: | Arabidopsis thaliana |
|---|
| Description: | ChEMBL_415082 |
|---|
| Residue: | 336 |
|---|
| Sequence: | MDLASNLGGKIDKSDVLTAVEKYEQYHVFHGGNEEERKANYTDMVNKYYDLATSFYEYGW
GESFHFAQRWKGESLRESIKRHEHFLALQLGIQPGQKVLDVGCGIGGPLREIARFSNSVV
TGLNNNEYQITRGKELNRLAGVDKTCNFVKADFMKMPFPENSFDAVYAIEATCHAPDAYG
CYKEIYRVLKPGQCFAAYEWCMTDAFDPDNAEHQKIKGEIEIGDGLPDIRLTTKCLEALK
QAGFEVIWEKDLAKDSPVPWYLPLDKNHFSLSSFRLTAVGRFITKNMVKILEYIRLAPQG
SQRVSNFLEQAAEGLVDGGRREIFTPMYFFLARKPE
|
|
|
|---|
| BDBM50195621 |
|---|
| n/a |
|---|
| Name | BDBM50195621 |
|---|
| Synonyms: | 3beta-acetoxy-23,24-bisnor-chol-5-en-22-(methyl heptanoate) amine | CHEMBL217321 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C32H53NO4 |
|---|
| Mol. Mass. | 515.7675 |
|---|
| SMILES | COC(=O)CCCCCCNC[C@@H](C)[C@H]1CC[C@H]2C3CC=C4C[C@H](CC[C@]4(C)[C@H]3CC[C@]12C)OC(C)=O |t:20| |
|---|
| Structure | 
|
|---|
Search and Browse
