| Reaction Details |
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 | Report a problem with these data |
| Target | Cycloartenol-C-24-methyltransferase |
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| Ligand | BDBM50195629 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_415082 (CHEMBL912396) |
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| IC50 | >100000±n/a nM |
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| Citation |  Gros, L; Lorente, SO; Jimenez, CJ; Yardley, V; Rattray, L; Wharton, H; Little, S; Croft, SL; Ruiz-Perez, LM; Gonzalez-Pacanowska, D; Gilbert, IH Evaluation of azasterols as anti-parasitics. J Med Chem49:6094-103 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cycloartenol-C-24-methyltransferase |
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| Name: | Cycloartenol-C-24-methyltransferase |
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| Synonyms: | 24-sterol C-methyltransferase | CPH | SMT1 | SMT1_ARATH |
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| Type: | PROTEIN |
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| Mol. Mass.: | 38266.01 |
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| Organism: | Arabidopsis thaliana |
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| Description: | ChEMBL_415082 |
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| Residue: | 336 |
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| Sequence: | MDLASNLGGKIDKSDVLTAVEKYEQYHVFHGGNEEERKANYTDMVNKYYDLATSFYEYGW
GESFHFAQRWKGESLRESIKRHEHFLALQLGIQPGQKVLDVGCGIGGPLREIARFSNSVV
TGLNNNEYQITRGKELNRLAGVDKTCNFVKADFMKMPFPENSFDAVYAIEATCHAPDAYG
CYKEIYRVLKPGQCFAAYEWCMTDAFDPDNAEHQKIKGEIEIGDGLPDIRLTTKCLEALK
QAGFEVIWEKDLAKDSPVPWYLPLDKNHFSLSSFRLTAVGRFITKNMVKILEYIRLAPQG
SQRVSNFLEQAAEGLVDGGRREIFTPMYFFLARKPE
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| BDBM50195629 |
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| n/a |
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| Name | BDBM50195629 |
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| Synonyms: | 3beta-acetoxy-23,24-bisnor-5-en-22-(3-(2-Boc-amino)propanoic acid) amine | CHEMBL217554 |
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| Type | Small organic molecule |
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| Emp. Form. | C32H52N2O6 |
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| Mol. Mass. | 560.7651 |
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| SMILES | C[C@H](CNC[C@H](NC(=O)OC(C)(C)C)C(O)=O)[C@H]1CC[C@H]2C3CC=C4C[C@H](CC[C@]4(C)[C@H]3CC[C@]12C)OC(C)=O |t:23| |
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| Structure | 
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