| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50196009 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_431897 (CHEMBL917395) |
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| Ki | 1.6±n/a nM |
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| Citation |  Giorgi, I; Bianucci, AM; Biagi, G; Livi, O; Scartoni, V; Leonardi, M; Pietra, D; Coi, A; Massarelli, I; Nofal, FA; Fiamingo, FL; Anastasi, P; Giannini, G Synthesis, biological activity and molecular modelling of new trisubstituted 8-azaadenines with high affinity for A1 adenosine receptors. Eur J Med Chem42:1-9 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | AA1R_BOVIN | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | ADORA1 | Adenosine A1 receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 36602.99 |
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| Organism: | BOVINE |
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| Description: | ADENOSINE 0 BOVINE::P28190 |
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| Residue: | 326 |
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| Sequence: | MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPRTYFHTCLKVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
PRRAVVAITGCWILSFVVGLTPMFGWNNLSAVERDWLANGSVGEPVIECQFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYMEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPSCHMPRILIYIAIFLSHGNSAMNPIVYAFRIQKFRVTFL
KIWNDHFRCQPAPPVDEDAPAERPDD
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| BDBM50196009 |
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| n/a |
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| Name | BDBM50196009 |
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| Synonyms: | 3-benzyl-N-cyclohexyl-5-phenyl-3H-[1,2,3]triazolo[4,5-b]pyridin-7-amine | CHEMBL427437 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H25N5 |
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| Mol. Mass. | 383.4888 |
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| SMILES | C(c1ccccc1)n1nnc2c(NC3CCCCC3)cc(nc12)-c1ccccc1 |
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| Structure | 
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