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TargetApoptosis regulator Bcl-2
LigandBDBM50196034
Substrate/Competitorn/a
Meas. Tech.ChEMBL_416888 (CHEMBL909444)
Ki 11±n/a nM
Citation Wang, GNikolovska-Coleska, ZYang, CYWang, RTang, GGuo, JShangary, SQiu, SGao, WYang, DMeagher, JStuckey, JKrajewski, KJiang, SRoller, PPAbaan, HOTomita, YWang, S Structure-based design of potent small-molecule inhibitors of anti-apoptotic Bcl-2 proteins. J Med Chem49:6139-42 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Apoptosis regulator Bcl-2
Name:Apoptosis regulator Bcl-2
Synonyms:Apoptosis regulator Bcl-2 Protein | B-cell lymphoma 2 protein (Bcl-2) | BCL-2 | BCL2 | BCL2_HUMAN | Bcl-2 Protein
Type:Homodimer or heterodimer
Mol. Mass.:26269.11
Organism:Homo sapiens (Human)
Description:P10415
Residue:239
Sequence:
MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDVGAAPPGAAPAPGIFSSQPGHTPHPA
ASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLH
LTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEY
LNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACITLGAYLGHK
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50196034
n/a
NameBDBM50196034
Synonyms:CHEMBL410802 | QEDIIRNIARHLAQVGDSMDR
TypeSmall organic molecule
Emp. Form.C100H169N35O34S
Mol. Mass.2437.691
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Structure
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