| Reaction Details |
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 | Report a problem with these data |
| Target | Sphingosine 1-phosphate receptor 5 |
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| Ligand | BDBM50133425 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_432839 (CHEMBL914107) |
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| EC50 | 480±n/a nM |
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| Citation |  Foss, FW; Snyder, AH; Davis, MD; Rouse, M; Okusa, MD; Lynch, KR; Macdonald, TL Synthesis and biological evaluation of gamma-aminophosphonates as potent, subtype-selective sphingosine 1-phosphate receptor agonists and antagonists. Bioorg Med Chem15:663-77 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sphingosine 1-phosphate receptor 5 |
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| Name: | Sphingosine 1-phosphate receptor 5 |
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| Synonyms: | EDG8 | Endothelial differentiation sphingolipid G-protein-coupled receptor 8 | S1P5 | S1PR5 | S1PR5_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-8 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 41796.42 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 398 |
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| Sequence: | MESGLLRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAVVCLAVCAFIVLENLAVLLV
LGRHPRFHAPMFLLLGSLTLSDLLAGAAYAANILLSGPLTLKLSPALWFAREGGVFVALT
ASVLSLLAIALERSLTMARRGPAPVSSRGRTLAMAAAAWGVSLLLGLLPALGWNCLGRLD
ACSTVLPLYAKAYVLFCVLAFVGILAAICALYARIYCQVRANARRLPARPGTAGTTSTRA
RRKPRSLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARTCPVLLQADPFLGLAMANSL
LNPIIYTLTNRDLRHALLRLVCCGRHSCGRDPSGSQQSASAAEASGGLRRCLPPGLDGSF
SGSERSSPQRDGLDTSGSTGSPGAPTAARTLVSEPAAD
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| BDBM50133425 |
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| n/a |
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| Name | BDBM50133425 |
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| Synonyms: | CHEMBL227371 | CHEMBL422074 | Phosphoric acid mono-[(R)-2-amino-2-(4-octyl-phenylcarbamoyl)-ethyl] ester; TFA |
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| Type | Small organic molecule |
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| Emp. Form. | C17H29N2O5P |
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| Mol. Mass. | 372.3963 |
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| SMILES | CCCCCCCCc1ccc(NC(=O)[C@H](N)COP(O)(O)=O)cc1 |
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| Structure | 
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