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TargetSphingosine 1-phosphate receptor 4
LigandBDBM50198839
Substrate/Competitorn/a
Meas. Tech.ChEMBL_432838 (CHEMBL914106)
EC50 440000±n/a nM
Citation Foss, FWSnyder, AHDavis, MDRouse, MOkusa, MDLynch, KRMacdonald, TL Synthesis and biological evaluation of gamma-aminophosphonates as potent, subtype-selective sphingosine 1-phosphate receptor agonists and antagonists. Bioorg Med Chem15:663-77 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Sphingosine 1-phosphate receptor 4
Name:Sphingosine 1-phosphate receptor 4
Synonyms:EDG6 | Endothelial differentiation G-protein coupled receptor 6 | S1P receptor 4 | S1P receptor Edg-6 | S1P4 | S1PR4 | S1PR4_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-6 | Sphingosine-1-phosphate receptor 4 | sphingosine-1-phosphate 4 S1P4
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:41647.39
Organism:Homo sapiens (Human)
Description:n/a
Residue:384
Sequence:
MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLV
VLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFL
REGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLP
LLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRP
AARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNS
AVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDS
FRGSRSLSFRMREPLSSISSVRSI
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  Blast E-value cutoff:
BDBM50198839
n/a
NameBDBM50198839
Synonyms:CHEMBL228137 | [3-hydroxy-4-(4-octylphenoxy)-butyl]-phosphonic acid
TypeSmall organic molecule
Emp. Form.C18H31O5P
Mol. Mass.358.4095
SMILESCCCCCCCCc1ccc(OC[C@@H](O)CCP(O)(O)=O)cc1
Structure
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