| Reaction Details |
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 | Report a problem with these data |
| Target | Tyrosine-protein kinase CSK |
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| Ligand | BDBM50200208 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_422673 (CHEMBL913341) |
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| IC50 | 3300±n/a nM |
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| Citation |  Gu, X; Wang, Y; Kumar, A; Ye, G; Parang, K; Sun, G Design and evaluation of hydroxamate derivatives as metal-mediated inhibitors of a protein tyrosine kinase. J Med Chem49:7532-9 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Tyrosine-protein kinase CSK |
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| Name: | Tyrosine-protein kinase CSK |
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| Synonyms: | C-SRC kinase | C-src tyrosine kinase | CSK | CSK_HUMAN | Protein-tyrosine kinase CYL | Tyrosine Kinase CSK |
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| Type: | Tyrosine-protein kinase |
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| Mol. Mass.: | 50707.30 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P41240 |
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| Residue: | 450 |
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| Sequence: | MSAIQAAWPSGTECIAKYNFHGTAEQDLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGII
PANYVQKREGVKAGTKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCV
SCDGKVEHYRIMYHASKLSIDEEVYFENLMQLVEHYTSDADGLCTRLIKPKVMEGTVAAQ
DEFYRSGWALNMKELKLLQTIGKGEFGDVMLGDYRGNKVAVKCIKNDATAQAFLAEASVM
TQLRHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCE
AMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGKLPVKWTAPEALRE
KKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVMK
NCWHLDAAMRPSFLQLREQLEHIKTHELHL
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| BDBM50200208 |
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| n/a |
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| Name | BDBM50200208 |
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| Synonyms: | (S)-2-amino-N-hydroxy-3-(4-isopropylphenyl)propanamide | CHEMBL218768 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H18N2O2 |
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| Mol. Mass. | 222.2835 |
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| SMILES | CC(C)c1ccc(C[C@H](N)C(=O)NO)cc1 |r| |
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| Structure | 
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