| Reaction Details |
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 | Report a problem with these data |
| Target | Nociceptin receptor |
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| Ligand | BDBM50200601 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_453746 (CHEMBL885746) |
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| Ki | 2±n/a nM |
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| Citation |  Palin, R; Bom, A; Clark, JK; Evans, L; Feilden, H; Houghton, AK; Jones, PS; Montgomery, B; Weston, MA; Wishart, G Synthesis and evaluation of N-3 substituted phenoxypropyl piperidine benzimidazol-2-one analogues as NOP receptor agonists with analgesic and sedative properties. Bioorg Med Chem15:1828-47 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Nociceptin receptor |
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| Name: | Nociceptin receptor |
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| Synonyms: | KOR-3 | Kappa-type 3 opioid receptor | Mu-type opioid receptor (Mu) | NOP | Nociceptin Receptor (ORL1 Receptor) | Nociceptin receptor (NOP) | Nociceptin receptor (ORL-1) | Nociceptin receptor (ORL1) | Nociceptin/Orphanin FQ, NOP receptor | OOR | OPIATE ORL-1 | OPRL1 | OPRL1 protein | OPRX_HUMAN | ORL1 | ORL1 receptor | Opioid receptor like-1 | Orphanin FQ receptor | Orphanin FQ receptor (ORL1) | P41146 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40702.87 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P41146 |
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| Residue: | 370 |
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| Sequence: | MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASHGAFLPLGLKVTIVGLYLA
VCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGN
ALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASV
VGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIR
RLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAI
LRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRDVQVSDRVRSIAKDVALAC
KTSETVPRPA
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| BDBM50200601 |
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| n/a |
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| Name | BDBM50200601 |
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| Synonyms: | 1-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-methylpentyl]-piperidin-4-yl}-3-(2-methylamino-ethyl)-1,3-dihydro-benzimidazol-2-one | CHEMBL240084 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H42N4O3 |
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| Mol. Mass. | 494.6688 |
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| SMILES | CNCCn1c2ccccc2n(C2CCN(CCC(Oc3cc(OC)ccc3C)C(C)C)CC2)c1=O |w:18.19| |
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| Structure | 
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