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TargetGag-Pol polyprotein [489-587]
LigandBDBM50200951
Substrate/Competitorn/a
Meas. Tech.ChEMBL_422734 (CHEMBL854830)
Ki 27±n/a nM
Citation Whiting, MTripp, JCLin, YCLindstrom, WOlson, AJElder, JHSharpless, KBFokin, VV Rapid discovery and structure-activity profiling of novel inhibitors of human immunodeficiency virus type 1 protease enabled by the copper(I)-catalyzed synthesis of 1,2,3-triazoles and their further functionalization. J Med Chem49:7697-710 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Gag-Pol polyprotein [489-587]
Name:Gag-Pol polyprotein [489-587]
Synonyms:Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:Enzyme Subunit
Mol. Mass.:10781.16
Organism:Human immunodeficiency virus type 1
Description:P04585[489-587]
Residue:99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50200951
n/a
NameBDBM50200951
Synonyms:CHEMBL267645 | cyclopentyl (2S,3S)-3-[4-([4-(2,5-dimethylphenyl)piperazin-1-yl]methyl)-5-[(S)-1-hydroxypropyl]-1H-1,2,3-triazol-1-yl]-1,4-diphenylbutan-2-ylcarbamate
TypeSmall organic molecule
Emp. Form.C40H52N6O3
Mol. Mass.664.8793
SMILESCC[C@H](O)c1c(CN2CCN(CC2)c2cc(C)ccc2C)nnn1[C@@H](Cc1ccccc1)[C@H](Cc1ccccc1)NC(=O)OC1CCCC1 |r|
Structure
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